publications

A text book (in german) for students who would like to get a first introduction into cellular biophysics

Biophysik in der Zelle

T. Bornschlögl and H. Dietz

Springer Spektrum, ISBN: 978-3-662-61608-6, (2021)

This article shows that long term exposure to physiological concentrations of airpollution correlates with detectable stuctural alterations within the hair fiber

Human pollution exposure correlates with accelerated ultrastructural degradation of hair fibers

G. Naudin, P. Bastien, S. Mezzache, E. Trehu, N. Bourokba, B. M. R. Appenzeller, J. Soeur and T. Bornschlögl

Proc. Natl. Acad. Sci. U S A, 116 (37), 18410-18415, (2019)

This article gives insight into the force production mechanisms of cellular "antennae" which could be used by the cell to sense the mechanics of its environent

Filopodial retraction force is generated by cortical actin dynamics and controlled by reversible tethering at the tip

T. Bornschlögl, S. Romero, C. Vestergaard, J-F Joanny, G. Tran Van Nhieu and P. Bassereau

Proc. Natl. Acad. Sci. U S A, 110(47), 18928, (2013)

This article shows that fluctuation theorems, which have been experimentally validated before using optical traps can also be applied to atomic force microscopy

Single molecule dynamics of mechanical coiled-coil unzipping

T. Bornschlögl and M. Rief

Langmuir, 24(4), 1338, (2008)

A publication showing the experimental feasability of mechanical unzipping of coiled coils using the atomic force microscope. This, together with a theoretical description based on a simplified partition function, allows to detect the impact of a single amino acid on the mechanical stability of the protein

Single molecule unzipping of coiled coils: sequence resolved stability profiles

T. Bornschlögl and M. Rief

Physical Review Letters, 96(11), 118102, (2006)

Rac1 activation can generate untemplated, lamellar membrane ruffles

F. Leyden, S. Uthishtran, U. K. Moorthi, H.M. York, A. Patil, H. Gandhi, E. P. Petrov, T. Bornschlögl and S. Arumugam

BMC Biology, 19, 72, (2021)

Human pollution exposure correlates with accelerated ultrastructural degradation of hair fibers

G. Naudin, P. Bastien, S. Mezzache, E. Trehu, N. Bourokba, B. M. R. Appenzeller, J. Soeur and T. Bornschlögl

Proc. Natl. Acad. Sci. U S A, 116 (37), 18410-18415, (2019)

In vivo quantitative molecular absorption of glycerol in human skin using coherent anti-Stokes Raman scattering (CARS) and two-photon auto-fluorescence

B. Sarri, X. Chen, R. Canonge, S. Grégoire, F. Formanek, J-B. Galey, A. Potter, T. Bornschlögl and H. Rigneault

Journal of Controlled Release , 308, 190-196 (2019)

Whole-GUV patch-clamping

M. Garten, L. D. Mosgaard, T. Bornschlögl, S. Dieudonné, P. Bassereau and G. ES Toombes

Proc. Natl. Acad. Sci. U S A, 114(2), 328-333, (2017)

Keratin network modifications lead to the mechanical stiffening of the hair follicle fiber

T. Bornschlögl, L. Bildstein, S. Thibaut, R. Santoprete, F. Fiat, G. S. Luengo, J. Doucet, B. A. Bernard, and N. Baghdadli

Proc. Natl. Acad. Sci. U S A, 113(21), 5940, (2016)

Dynamics of Membrane Tethers Reveal Novel Aspects of Cytoskeleton-Membrane Interactions in Axons

A. Datar, T. Bornschlögl, P. Bassereau, J. Prost and P. A. Pullarkat

Biophysical Journal, 108(3), 489, (2015)

Filopodial retraction force is generated by cortical actin dynamics and controlled by reversible tethering at the tip

T. Bornschlögl, S. Romero, C. Vestergaard, J-F Joanny, G. Tran Van Nhieu and P. Bassereau

Proc. Natl. Acad. Sci. U S A, 110(47), 18928, (2013)

Filopodium retraction is controlled by adhesion to its tip

S. Romero*, A. Quatela*, T. Bornschlögl*, S. Guadagnini, P. Bassereau and G. Tran Van Nhieu

Journal of Cell Science,125(21), 4999, (2012)

Full distance-resolved folding energy landscape of one single protein molecule

J. C. Gebhardt, T. Bornschlögl and M. Rief

Proc. Natl. Acad. Sci. U S A,107(5), 2013, (2010)

Designing the folding mechanics of coiled coils

T. Bornschlögl, J. C. Gebhardt and M. Rief

ChemPhysChem, 10(16), 2800, (2009)

Single molecule mechanics of the kinesin neck

T. Bornschlögl, G. Woehlke and M. Rief

Proc. Natl. Acad. Sci. U S A, 106(17), 6992, (2009)

Tightening the knot in phytochrome by single molecule atomic force microscopy

T. Bornschlögl, D. M. Anstrom, E. Mey, J. Dzubiella, M. Rief and K. Forest

Biophysical Journal, 96(4), 1508, (2009)

Single molecule dynamics of mechanical coiled-coil unzipping

T. Bornschlögl and M. Rief

Langmuir, 24(4), 1338, (2008)

Programming protein self-assembly with coiled coils

H. Dietz*, T. Bornschlögl*, R. Heym, F. König, and M. Rief

New Journal of Physics, 9, 424, (2007)

Cysteine engineering of polyproteins for single molecule force spectroscopy

H. Dietz, M. Bertz, M. Schlierf, F. Berkemeier, T. Bornschlögl, J. Junker, and M. Rief

Nature Protocols, 1(1), 80, (2006)

Single molecule unzipping of coiled coils: sequence resolved stability profiles

T. Bornschlögl and M. Rief

Physical Review Letters, 96(11), 118102, (2006)

Biophysik in der Zelle

T. Bornschlögl and H. Dietz

Springer Spektrum, ISBN: 978-3-662-61608-6, (2021)

Imaging and quantifying drug delivery in skin – Part 1: Autoradiography and mass spectrometry imaging

S. Grégoire, G. S. Luengo, P. Hallegot, A.-M. Pena, X. Chen, T. Bornschlögl, K. F. Chan, I. Pence, P. Obeidy, A. Feizpour, S. Jeong and C. L. Evans

Advanced drug delivery reviews, 153, 137-146, (2020)

Imaging and quantifying drug delivery in skin – Part 2: Fluorescence and vibrational spectroscopic imaging methods

A.-M. Pena, X. Chen, I. Pence, T. Bornschlögl, S. Jeong, S. Grégoire, G. S. Luengo, P. Hallegot, P. Obeidy, A. Feizpour, K. F. Chan and C. L. Evans

Advanced Drug Delivery Reviews, 153, 147-168, (2020)

How filopodia pull: What we know about the mechanics and dynamics of filopodia

T. Bornschlögl

Cytoskeleton, 70(10), 590, (2013)

The sense is in the fingertips. The distal end controls filopodial mechanics and dynamics in response to external stimuli

T. Bornschlögl and P. Bassereau

Communicative and Integrative Biology, 6(6), e27341 (2013)

Single molecule protein unfolding and refolding using atomic force microscopy

T. Bornschlögl and M. Rief

Methods in Molecular Biology, 783, 233 (2011)

Gleichgewichtsmechanik und Fluktuationen von Superhelices

T. Bornschlögl

Cuvillier Verlag Göttingen, ISBN: 978-3-86727-814-0, (2008)

Kraftspektroskopische Untersuchungen an coiled-coil Strukturen

T. Bornschlögl

Master Thesis, Ludwig Maximilians Universität München (2004)